Original description as Characodon eiseni:
- Rutter, Cloudsley M. 1896. "Notes on fresh water fishes of the Pacific slope of North America. II. The fishes of Rio Yaqui, Sonora, with the description of a new genus of Siluridae". Proceedings of the California Academy of Sciences. 6:255-262 (ffm04522)
Conservation: Xenotoca eiseni is evaluated by the international union for the conservation of nature in the iucn red list of threatened species as (EN) endangered (2018). Xenotoca eiseni is potentially threatened by habitat loss and degradation caused by sedimentation, chemical pollution, overextraction of water resources, competition and predation from invasive alien species and anthropogenic modifications to flow regimes (from Köck, 2019). Many populations have disappeared owing to lack of water, habitat destruction, and introductions of non-native species, and only a handful of small populations remain. X. eiseni survives in small numbers in just a few springs and streams (Lyons et al., 2019:144).